Prediction of Clinical Outcome in Islet Allotransplantation
نویسندگان
چکیده
منابع مشابه
Prediction of clinical outcome in islet allotransplantation.
R ecent progresses in the pancreas’ enzymatic digestion process along with novel immunosuppression strategies have led to successful clinical trials of islet transplantation in humans. On the other hand, clinical outcome remains variable and unpredictable in centers with limited experience. The possibility of predicting in vivo islet graft function should allow the selection of preparations on ...
متن کاملDetection of pancreatic islet tissue following islet allotransplantation in man.
Qualitative and quantitative standards have been recently proposed for islet isolation asaeument in humans and large animals ( 1). The ultimate test of viability is functional activity after transplantation into a diabetic recipient. Morphologic identification of insulin-containing transplanted islets could provide important correlative data and eventually confmn the functional results. Recentl...
متن کاملHuman islet allotransplantation in 18 diabetic patients.
Nineteen mtrahepatic islet allografts were performed in 18 patients. In group I. nine patients aged 8 to 58 years underwent (ombined liver-Islet allotransplantation following upper-abdominal exenteration for tumors too extensive to be removed with less drastic procedures.b•7 Preliminary results on these patients have been reponed previously.~ In group 2. three type I diabetic patients aged 22 t...
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This report provides our initial experience on islet isolation and intrahepatic allotransplantation in 20 patients. In Group 1, 10 patients underwent combined liver-islet allotransplantation following upper-abdominal exenteration for cancer. One patient underwent pancreatic islet allograft after near total pancreatectomy for chronic pancreatitis. In Group 2, 3 Type I diabetic patients received ...
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ژورنال
عنوان ژورنال: Diabetes Care
سال: 2007
ISSN: 0149-5992,1935-5548
DOI: 10.2337/dc06-1233